AFP Peptizyde was developed in response to parents' requests for a high DPP IV-containing enzyme product that did not include fruit-based enzymes such as papain or bromelain. Like Peptizyde, it is a combination of three different proteolytic enzymes isolated from fungal plant sources. Each enzyme has a unique set of peptide bonds it prefers to break, so the combination of these enzymes allows much more efficient means of quickly and thoroughly breaking down (hydrolyzing) proteins into smaller components.

The enzymes in AFP Peptizyde work only on food proteins, not carbohydrates, fats, or other compounds, and do not interfere with medications or other supplements (unless they are also proteins, which is extremely unlikely). AFP Peptizyde may be used in combination with other enzyme products, such as Zyme Prime or No-Fenol. If undecided as to use Peptizyde or AFP Peptizyde, opt for AFP Peptizyde due to it having no odour/taste or papain.